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Regulation of gene expression by the CYP27B1 promoter—study of a transgenic mouse model

✍ Scribed by Ivanka Hendrix; Paul Anderson; Brian May; Howard Morris

Book ID
116697394
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
62 KB
Volume
89-90
Category
Article
ISSN
0960-0760

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## Abstract Hypoxic injury to the ocular surface provokes an inflammatory response that is mediated, in part, by corneal epithelial‐derived 12‐hydroxyeicosanoids. Recent studies indicate that a cytochrome P450 (CYP) monooxygenase, identified as CYP4B1, is involved in the production of these eicosan