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Regulation of GAD expression in rat pancreatic islets and brain by γ-vinyl-GABA and glucose

✍ Scribed by J. S. Petersen; K. Rimvall; P. N. Jørgensen; E. Hasselager; A. Moody; K. Hejnæs; J. T. Clausen; T. Dyrberg


Book ID
105821926
Publisher
Springer
Year
1998
Tongue
English
Weight
507 KB
Volume
41
Category
Article
ISSN
0012-186X

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Previous studies have demonstrated that the expression of one of the isoforms of glutamate decarboxylase, GAD 67 , is selectively reduced in cultured cortical neurons and in rat cerebral cortex when the concentration of GABA is elevated. We asked whether the expression of GAD 67 was similarly affect