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Regulation of FGF receptor-2 expression by transcription factor E2F-1

✍ Scribed by Tashiro, Etsu; Minato, Yusuke; Maruki, Hiroko; Asagiri, Masataka; Imoto, Masaya

Book ID: 118676935
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 213 KB
Volume: 22
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1206636

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## Abstract Epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is frequently over‐expressed in human cancers and is associated with tumorigenesis, and increased tumor proliferation and progression. Also found in breast tumors with high levels is B‐Myb, a transcription factor