## Abstract Macrophages/microglia are the key effector cells in myelin removal. Differences exist in the amount and time course of myelin uptake in the central (CNS) and peripheral nervous system (PNS), the basis of this difference, however, is not yet clarified. In the present experiments we studi
Regulation of Fcγ receptors and immunoglobulin G-mediated phagocytosis in mouse microglia
✍ Scribed by Yi Quan; Thomas Möller; Jonathan R. Weinstein
- Book ID
- 116771651
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 335 KB
- Volume
- 464
- Category
- Article
- ISSN
- 0304-3940
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Normal and stimulated macrophage populations induced by six different stimuli were tested for their IgG and complement (C)‐mediated phagocytic capacity. A similar phagocytic capacity for sheep red cells (E) coated with IgG was exhibited by normal and stimulated macrophage populations wi
Receptors for the Fc portion of immunoglobulin G (IgG; FcgammaRs) facilitate IgG uptake by effector cells as well as cellular responses initiated by IgG binding. In earlier studies, we demonstrated that amyotrophic lateral sclerosis (ALS) patient IgG can be taken up by motor neuron terminals and tra