Regulation of experimental allergic encephalomyelitis III. Demonstration of effector cells in tolerant rats
โ Scribed by James H. Holda; Robert H. Swanborg
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 329 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0014-2980
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๐ SIMILAR VOLUMES
## Abstract Relatively low numbers of spleen and lymph node cells from Lewis rats previously challenged with myelin basic protein efficiently transfer experimental allergic encephalomyelitis (EAE) to normal syngeneic recipients after __in vitro__ culture with antigen. Moreover, cells obtained from
Rats of the Fischer 344 (F344) strain are resistant to experimental allergic encephalomyelitis (EAE) induced by active immunization with guinea pig myelin basic protein (MBP) in complete Freund's adjuvant whereas Lewis (LEW) rats are susceptible even though both strains share the same I-A-like class