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Regulation of epidermal growth factor binding in a human keratinocyte cell line by 2,3,7,8-tetrachlorodibenzo-p-dioxin

โœ Scribed by Laurie G. Hudson; William A. Toscano Jr.; William F. Greenlee


Book ID
113206571
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
747 KB
Volume
77
Category
Article
ISSN
0041-008X

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2,3,7,8-tetrachlorodibenzo-p- dioxin red
โœ Moriya, Masaaki ;Matsumura, Fumio ;Kalimi, Ghulm H. ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 538 KB

The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on epidermal growth factor (EGF)-binding characteristics was studied in a cultured embryonic fibroblast cell line, C3H 10T1/2. At very low concentrations, TCDD was found to cause a persistent decline in EFG binding, the median effective concen