c-jun-NH2JNK mediates invasive potential
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Mónica Cáceres; Nicolás Tobar; Javier Guerrero; Patricio C. Smith; Jorge Martíne
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Article
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2008
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John Wiley and Sons
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English
⚖ 203 KB
## Abstract In this study, we demonstrated that tyrosine phosphorylation of EGFR and the autocrine expression of uPA and HB‐EGF depend on the activity of c‐jun amino‐terminal kinase (JNK) in human prostatic DU‐145 cells. These cells overexpress EGFR and produce a high amount of uPA. Treatment with