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Regulation of effectors by G-protein α- and βγ-Subunits: Recent insights from studies of the phospholipase C-β isoenzymes

✍ Scribed by Andrew J. Morris; Suzanne Scarlata

Book ID
119407265
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
856 KB
Volume
54
Category
Article
ISSN
0006-2952

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G, and G,, respectively, activate and inhibit the enzyme adenylyl cyclase. Regulation of adenylyl cycldse by the heterotrimeric G, and G, proteins requires the dissociation of GDP and binding of GTP to the a, or a, subunit. The 0-y subunit complex of G, and G, functions, in part, to inhibit GDP diss