𝔖 Bobbio Scriptorium
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Regulation of drosophila folylpolyglutamates during development

✍ Scribed by Edward J. Duke; David G. Priest

Book ID
104669770
Publisher
Springer
Year
1990
Tongue
English
Weight
174 KB
Volume
97
Category
Article
ISSN
0300-8177

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✦ Synopsis

The polyglutamate status of reduced folates during the larval, pupal and adult stages of Drosophila melanogaster development was investigated. The chain length distribution is very similar and is predominantly pentaglutamate. Half-life estimates of the hydrolytic degradation to the monoglutamate showed larva less than pupa less than adult. This raises the possibility that polyglutamate hydrolase may have a role in regulating the total intracellular reduced folate content of the different developmental stages.

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