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Regulation of Double-Stranded RNA Dependent Protein Kinase Expression and Attenuation of Protein Synthesis Induced by Bacterial Toll-Like Receptors Agonists in the Absence of Interferon

✍ Scribed by Sales, Paula C.M.; Williams, Bryan R.G.; Silva, Aristóbolo M.


Book ID
115313693
Publisher
Mary Ann Liebert
Year
2012
Tongue
English
Weight
550 KB
Volume
32
Category
Article
ISSN
1079-9907

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## Abstract ## Objective To assess the presence of Toll‐like receptors (TLRs) 1–9 in human articular cartilage, and to investigate the effects of lipopolysaccharide (LPS)–induced activation of TLR‐4 on biosynthetic activity and matrix production by human articular chondrocytes. ## Methods TLRs 1