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Regulation of DNA-replication origins during cell-cycle progression

✍ Scribed by Yoshikawa, Hiroshi; Shirahige, Katsuhiko; Hori, Yuji; Shiraishi, Katsuya; Yamashita, Minoru; Takahashi, Keiko; Obuse, Chikashi; Tsurimoto, Toshiki


Book ID
109707586
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
401 KB
Volume
395
Category
Article
ISSN
0028-0836

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A computer simulation is presented for cell proliferation in a structured cell cycle model. The simulation takes into account the idea that DNA replication and cell growth are two loosely coupled subcycles. The simulation experiments performed offer an explanation for the close correlation often fou