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Regulation of DISC1 through phosphorylation by ERK

✍ Scribed by Shinichiro Taya; Junko Uraguchi-Asaki; Keisuke Kuroda; Kozo Kaibuchi


Book ID
116775759
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
95 KB
Volume
58
Category
Article
ISSN
0168-0102

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## Abstract Numerous studies have shown that mammalian target of rapamycin (mTOR) inhibitor activates Akt signaling pathway via a negative feedback loop while inhibiting mTORC1 signaling. In this report, we focused on studying the role of mTORC1 and mTORC2 in rapamycin‐mediated Akt and ERK phosphor