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Regulation of differential pro- and anti-apoptotic signaling by glucocorticoids

✍ Scribed by Ingrid Herr; Nikolaus Gassler; Helmut Friess; Markus W. Büchler


Book ID
106349401
Publisher
Springer
Year
2006
Tongue
English
Weight
831 KB
Volume
12
Category
Article
ISSN
1360-8185

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The gene encoding pro-opiomelanocortin (POMC) offers an interesting model system to study negative control of transcription in eucaryotes. Indeed, glucocorticoid hormones specifically inhibit transcription of the POMC gene in the anterior pituitary. The POMC gene is predominantly expressed in the an