Regulation of cytosolic phosphoenolpyruvate carboxykinase gene expression in adipocytes
โ Scribed by Elmus G. Beale; Claude Forest; Robert E. Hammer
- Book ID
- 116308254
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 246 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0300-9084
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Glucocorticoids exert pleiotropic effects, among which negative regulation of transcription has been recognized as of crucial importance. While glucocorticoids induce phosphoenolpyruvate carboxykinase (PEPCK) gene expression in liver cells, it represses gene activity in adipose cells. We used the 3T
Phosphoenolpyruvate carboxykinase (PEPCK) exerts a glyceroneogenic function in adipocytes in which transcription of its gene is increased by unsaturated fatty acids and fibrates. We used cultured rat adipose tissue fragments and 3T3-F442A adipocytes to show that the antidiabetic thiazolidinedione BR