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Regulation of cytoplasmic pH in resident and activated peritoneal macrophages

✍ Scribed by Carol J Swallow; Sergio Grinstein; Ori D Rotstein


Book ID
115729323
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
816 KB
Volume
1022
Category
Article
ISSN
0005-2736

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Relative roles of Na+/H+ exchange and va
✍ Carol J. Swallow; Sergio Grinstein; Rae A. Sudsbury; Ori D. Rotstein πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 959 KB

Two distinct mechanisms have been shown to mediate cytoplasmic p H (pH,) recovery in acid-loaded peritoneal macrophages (M+s): Na+/H+ exchange and H + extrusion by vacuolar-type (V-type) H+ ATPases. The present studies examined the relative roles of these two systems in maintaining pH, and cell func