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Regulation of cyclin B1, cyclin B2 and cdc25C genes by the tumor suppressor protein p53 and by p73 in colorectal adenocarcinoma cells mediating G2 cell cycle arrest

โœ Scribed by Engeland, Kurt; Krause, Karen; Dietz, Sebastian; Tannapfel, Andrea; Wittekind, Christian; Mossner, Joachim


Book ID
124129337
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
179 KB
Volume
120
Category
Article
ISSN
0016-5085

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Genes encoding cdkl (~34'~''), cyclin A, cyclin B, and the tumor suppressor gene Rb are fundamental regulators of cell cycle progression which associate as a complex with the transcription factor E2F. Expression of many of these proteins has previously been shown to be repressed by okadaic acid, a s