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Regulation of Current Flow through Ryanodine Receptors by Luminal Ca2+

โœ Scribed by R. Sitsapesan; A.J. Williams


Publisher
Springer
Year
1997
Tongue
English
Weight
328 KB
Volume
159
Category
Article
ISSN
0022-2631

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## Abstract Studies with inโ€vitroโ€cultured neurons treated with amyloidโ€ฮฒ (Aฮฒ) peptides demonstrated neuronal loss by apoptosis that is due, at least in part, to the perturbation of intracellular Ca^2+^ homeostasis. In addition, it was shown that an endoplasmic reticulum (ER)โ€specific apoptotic pat