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Regulation of chromatin structure via histone post-translational modification and the link to carcinogenesis

✍ Scribed by Thompson, Laura L.; Guppy, Brent J.; Sawchuk, Laryssa; Davie, James R.; McManus, Kirk J.


Book ID
121597284
Publisher
Springer
Year
2013
Tongue
English
Weight
361 KB
Volume
32
Category
Article
ISSN
0167-7659

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## Abstract The core histones are the primary protein component of chromatin, which is responsible for the packaging of eukaryotic DNA. The NH~2~‐terminal tail domains of the core histones are the sites of numerous post‐translational modifications that have been shown to play an important role in t