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Regulation of Cell Proliferation by Insulin-like Growth Factor 1 in Hyperoxia-Exposed Neonatal Rat Lung

โœ Scribed by Anne Chetty; Heber C. Nielsen


Book ID
115639966
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
432 KB
Volume
75
Category
Article
ISSN
1096-7192

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Insulin-like growth factor-ll (IGF-II) receptors in primary cultures of adult rat hepatocytes were characterized and their regulation by cell density examined. In hepatocytes cultured at 5 x lo5 cells per 3.8 cm2 plate, ['251]ICF-ll bound to specific, high affinity receptors (Ka = 4.4 + 0.5 x lo9 I