𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS)

✍ Scribed by Tyler R Simpson; Sergio A Quezada; James P Allison

Book ID
108099657
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
246 KB
Volume
22
Category
Article
ISSN
0952-7915

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

CD152 (CTLA-4) regulates effector functi
CD152 (CTLA-4) regulates effector functions of CD8+ T lymphocytes by repressing Eomesodermin
✍ Johannes K. Hegel; Karin Knieke; Paula Kolar; Steven L. Reiner; Monika C. Brunne 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB

## Abstract CD8^+^ T lymphocytes are required for effective host defense against pathogens and also for mediating effector responses against uncontrolled proliferating self‐tissues. In this study, we determine that individual CD8^+^ T cells are tightly controlled in their effector functions by CD15

Necrotic death but not irradiation aboli
Necrotic death but not irradiation abolishes costimulation of T-cell effector functions and survival by CD80-expressing tumor cells
✍ Lilian Stärck; Christian Scholz; Thomas Blankenstein; Bernd Dörken; Peter T. Dan 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 453 KB

## Abstract Tumor vaccination by the use of gene‐modified cancer cells that provide costimulatory signals has been successfully applied in preclinical animal models and is currently evaluated in a variety of clinical settings. In previous work, we demonstrated the efficacy of B7.1/CD80 to promote t