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Regulation of caspase activation in axotomized retinal ganglion cells

✍ Scribed by Zelda H Cheung; Yuen-Man Chan; Flora K.W Siu; Henry K Yip; Wutian Wu; Mason C.P Leung; Kwok-Fai So

Book ID: 116735143
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 516 KB
Volume: 25
Category: Article
ISSN: 1044-7431
DOI: 10.1016/j.mcn.2003.11.001

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## Abstract Autophagy has been shown to be activated in neuronal cells in response to injury and suggested to have a cell‐protective role in neurodegenerative diseases. In this study, we investigated the activation of autophagy in retinal ganglion cells (RGCs) following optic nerve transection (ONT