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Regulation of Ca2+-induced permeability transition by Bcl-2 is antagonized by Drp1 and hFis1

✍ Scribed by Dejuan Kong; Liping Xu; Yingjie Yu; Weijia Zhu; David W. Andrews; Yisang Yoon; Tuan H. Kuo

Book ID: 106457645
Publisher: Springer
Year: 2005
Tongue: English
Weight: 523 KB
Volume: 272
Category: Article
ISSN: 0300-8177
DOI: 10.1007/s11010-005-7323-3

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## Abstract ## Objective Rheumatoid arthritis (RA) synovial hyperplasia is related in part to a resistance to apoptosis exhibited by fibroblast‐like synoviocytes (FLS). Since hypoxia is a regulator of apoptosis, and since RA synovium is hypoxic, we conducted this study to examine the effects of hy