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Regulation of biosynthesis of aminoacyl-tRNA synthetases and of tRNA in Escherichia coli: III. Biochemical characterization of regulatory mutants affecting leucyl-tRNA synthetase levels

✍ Scribed by Robert A. LaRossa; Jen-i Mao; K. Brooks Low; Dieter Söll


Book ID
119443477
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
603 KB
Volume
117
Category
Article
ISSN
0022-2836

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Regulation of the biosynthesis of aminoa
✍ Theall, Gail ;Low, K. Brooks ;Söll, Dieter 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 556 KB

Spontaneous revertants of a temperature-sensitive Escherichia coli strain harboring a thermolabile leucyl-tRNA synthetase and seryl-tRNA synthetase were selected for growth at 40 degrees C. Among these, strains were found with increased levels of both thermolabile synthetases. Two distinct genetic l