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Regulation of aromatase P450 promoter (II) activity in endometriotic stromal cells by CCAAT/enhancer binding proteins (C/EBPs).

✍ Scribed by S Yang; Z Fang; J Zhou; B Gurates; M Tamara; S.E Bulun

Book ID: 119417457
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 25 KB
Volume: 76
Category: Article
ISSN: 1556-5653
DOI: 10.1016/s0015-0282(01)02149-5

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## Abstract CCAAT/enhancer binding protein δ (C/EBPδ) plays a key role in mammary epithelial cell G~0~ growth arrest. C/EBPδ gene expression is down‐regulated in rodent mammary tumorigenesis and in human breast cancer, suggesting that “loss of function” alterations in C/EBPδ gene expression are com