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Regulation of Armadillo by a Drosophila APC Inhibits Neuronal Apoptosis during Retinal Development

โœ Scribed by Yashi Ahmed; Shigemi Hayashi; Arnold Levine; Eric Wieschaus


Book ID
117268234
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
886 KB
Volume
93
Category
Article
ISSN
0092-8674

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Nerve growth factor (NGF), signaling through its receptor tyrosine kinase, TrkA, is required for the survival of all small and many intermediate-sized murine dorsal root ganglion (DRG) neurons during development, accounting for 80% of the total DRG population. Surprisingly, NGF/TrkA-dependent neuron