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Regulation of apolipoprotein A-I gene expression by phenobarbital in the human hepatocarcinoma cell line, Hep3B

โœ Scribed by Shul-Pang Tam; Roger G. Deeley


Book ID
118324575
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
900 KB
Volume
105
Category
Article
ISSN
0021-9150

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In situ hybridization and Northern analysis of heme oxygenase (HO) mRNA was used to determine the induction and expression of HO by various environmental agents. Exposure of Hep3B cells to hemin (1 0 pM) for as little as 5 min resulted in significant production of HO transcripts and mRNA expression