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Regulation of Alternative Splicing by Histone Modifications

โœ Scribed by Luco, R. F.; Pan, Q.; Tominaga, K.; Blencowe, B. J.; Pereira-Smith, O. M.; Misteli, T.


Book ID
118250267
Publisher
American Association for the Advancement of Science
Year
2010
Tongue
English
Weight
535 KB
Volume
327
Category
Article
ISSN
0036-8075

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Histone acetylation and phosphorylation destablizes nucleosome and chromatin structure. Relaxation of the chromatin fiber facilitates transcription. Coactivator complexes with histone acetyltransferase activity are recruited by transcription factors bound to enhancers or promoters. The recruited his