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Regulation of Actin Filament Assembly by Arp2/3 Complex and Formins

✍ Scribed by Pollard, Thomas D.


Book ID
111880032
Publisher
Annual Reviews
Year
2007
Tongue
English
Weight
1009 KB
Volume
36
Category
Article
ISSN
1056-8700

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## Abstract We review recent structural and biophysical studies of the mechanism of action of formins, proteins that direct the assembly of unbranched actin filaments for cytokinetic contractile rings and other cellular structures. Formins use free actin monomers to nucleate filaments and then rema