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Regulation of a Calcium-sensitive K+ Channel (cIK1) by Protein Kinase C

✍ Scribed by A. Wulf; A. Schwab

Publisher: Springer
Year: 2002
Tongue: English
Weight: 207 KB
Volume: 187
Category: Article
ISSN: 0022-2631
DOI: 10.1007/s00232-001-0149-3

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## Abstract By using pharmacological and molecular approaches, we previously showed that the G‐protein‐coupled, extracellular calcium (Ca)‐sensing receptor (CaR) regulates a large‐conductance (∼140 pS), Ca^2+^‐activated K^+^ channel [I~K(Ca)~; CAKC] in U87 astrocytoma cells. Here we show that eleva