Regulation mechanism of the expression of MEPE by BMP-2
✍ Scribed by Y. Cho; W. Yoon; H. Ryoo⁎
- Book ID
- 116321671
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 39 KB
- Volume
- 44
- Category
- Article
- ISSN
- 8756-3282
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## Abstract Bone morphogenetic proteins (BMPs) are members of the transforming growth factor‐beta (TGF‐β) gene superfamily of growth and differentiation factors. Members of the BMP family were originally cloned and characterized by their ability to induce ectopic bone formation. Of the various BMPs
## Abstract __M__atrix __e__xtracellular __p__hosphoglycoprot__e__in (MEPE) is a specific marker of mineralizing osteoblasts and osteocytes. Canonical BMP and Wnt signaling pathways are two of the strongest paracrine signals stimulating osteogenesis. Our previous results indicated that __Mepe__ exp