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Regulation by heavy metals and temperature of the human BAG-3 gene, a modulator of Hsp70 activity

✍ Scribed by Maria Gabriella Pagliuca; Rosa Lerose; Stefania Cigliano; Arturo Leone


Book ID
117105274
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
282 KB
Volume
541
Category
Article
ISSN
0014-5793

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## Abstract The goal of the investigation was to test the hypothesis that the phosphoinositide‐3 kinase (PI3K)/AKT signaling pathway regulates the expression of the major extracellular matrix component of the intervertebral disc, aggrecan, in nucleus pulposus cells. Primary rat nucleus pulposus cel