## Abstract Embryonic stem cells (ESCs) are pluripotent, selfβrenewing cells. These cells can be used in applications such as cell therapy, drug development, disease modeling, and the study of cellular differentiation. Investigating the interplay of epigenetics, genetics, and gene expression in con
Regulation beyond genome sequences: DNA and histone methylation in embryonic stem cells
β Scribed by Wei Yang; Qi Zhou; Xiu-Jie Wang
- Publisher
- SP Higher Education Press
- Year
- 2010
- Tongue
- English
- Weight
- 218 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1674-7984
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Rapid selfβrenewal of human embryonic stem (ES) cells (NIH designation WA01 and WA09) is accommodated by an abbreviated cell cycle due to a reduction in the G1 phase. Thus, molecular mechanisms operative in ES cells may expedite the cellular commitment to progress into S phase to initia
## Abstract Human embryonic stem (ES) cells have an expedited cell cycle (βΌ15 h) due to an abbreviated G1 phase (βΌ2.5 h) relative to somatic cells. One principal regulatory event during cell cycle progression is the G1/S phase induction of histone biosynthesis to package newly replicated DNA. In so