Regulation and Deregulation of E2F1 in Postmitotic Neurons Differentiated from Embryonal Carcinoma P19 Cells
β Scribed by Mizuki Azuma-Hara; Hideo Taniura; Taichi Uetsuki; Michio Niinobe; Kazuaki Yoshikawa
- Book ID
- 115603401
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 346 KB
- Volume
- 251
- Category
- Article
- ISSN
- 0014-4827
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The P19 embryonal carcinoma cell line represents a pluripotential stem cell that can differentiate along the neural or muscle cell lineage when exposed to different environments. Exposure to retinoic acid induces P19 cells to differentiate into neurons and astrocytes that express similar development
## Abstract Although primary neuronal cell cultures, usually obtained from embryonic or early postnatal rodents, have been used in vitro to study the neural cannabinoid signalling system, development of cell lines with neural properties exhibiting native expression of cannabinoid receptors is desir