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Regulating gene transcription in response to cyclic AMP elevation

✍ Scribed by William A. Sands; Timothy M. Palmer

Book ID
113528140
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
234 KB
Volume
20
Category
Article
ISSN
0898-6568

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The treatment of rat glioma C6 cells with 10 pM isoproterenol (Ipt) for 4 days upregulated the expression of the myelin-associated glycoprotein (MAG) gene by approximately 55-fold over the control value. The constant presence of Ipt in the medium was required for the maximal upregulation, as time-re