To prevent uncontrolled expansion, the massive proliferation of T cells during an acute immune response has to be followed by controlled deletion. Here we show that similar to Fas, perforin is not only an important effector molecule of cytotoxic T lymphocytes (CTL) but also involved in down-regulati
Regulating functional cell fates in CD8 T cells
โ Scribed by Protul A. Shrikant; Rajesh Rao; Qingsheng Li; Joshua Kesterson; Cheryl Eppolito; Axel Mischo; Pankaj Singhal
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 266 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0257-277X
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