Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins
โ Scribed by Randy D. Blakely; Sammanda Ramamoorthy; Sally Schroeter; Yan Qian; Subramaniam Apparsundaram; Aurelio Galli; Louis J. DeFelice
- Book ID
- 118512455
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 121 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0006-3223
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Modification of the transport velocity of both the native neuronal and cloned presynaptic dopamine transporter (DAT) has been reported following activation/inhibition of second messenger system pathways. In order to identify the mechanism by which the functional activity of human DAT (hDAT) is regul
## Abstract Protein kinases are critical component in the regulation of signal transduction pathways, including neurotransmitters. Our previous studies have shown that serotonin (5โHT) altered under diabetic condition was accompanied by alterations of protein kinase Cโฮฑ (PKCโฮฑ) and CaMKII, and thos