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Regulated expression of a transfected diphtheria toxin gene as a novel mechanism for killing tumour cells

✍ Scribed by Michael Glode, L.; Maxwell, Ian H.; Maxwell, Francoise; Sitarik, Mark; Kallio, Arja; Ulmanen, Ismo


Book ID
122626228
Publisher
Elsevier Science
Year
1987
Weight
119 KB
Volume
23
Category
Article
ISSN
0277-5379

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Transfectant mosaic spheroids: a new mod
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## Abstract ## Background We describe an __in vitro__ tumour model for targeted radiotherapy and gene therapy that incorporates cell population heterogeneity. ## Materials and methods Transfectant mosaic spheroids (TMS) and transfected mosaic monolayers (TMM) are composed of two cell populations