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Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation

✍ Scribed by Gian Luca Forni; Manuela Balocco; Laura Cremonesi; Giovanni Abbruzzese; Roberto Carlo Parodi; Roberta Marchese

Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 185 KB
Volume: 23
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.22002

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✦ Synopsis

Abstract

We report the results of iron chelating treatment with deferiprone in a 61‐year‐old woman with signs and symptoms of neurodegeneration with brain iron accumulation (NBIA). After 6 months of therapy the patient's gait had improved and a reduction in the incidence of choreic dyskinesias was observed. Her gait returned to normal after an additional 2 months of therapy, at which time there was a further reduction in involuntary movements and a partial resolution of the blepharospasm. © 2008 Movement Disorder Society

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