Regression of high-grade cervical intraepithelial neoplasia with TG4001 targeted immunotherapy
✍ Scribed by Jean-Luc Brun; Véronique Dalstein; Jean Leveque; Patrice Mathevet; Patrick Raulic; Jean-Jacques Baldauf; Suzy Scholl; Bernard Huynh; Serge Douvier; Didier Riethmuller; Christine Clavel; Philippe Birembaut; Valérie Calenda; Martine Baudin; Jean-Paul Bory
- Book ID
- 113436742
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 649 KB
- Volume
- 204
- Category
- Article
- ISSN
- 1097-6868
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## Abstract ## Background and Objectives To determine the safety and efficacy of 5‐aminolevulinic acid (ALA) as a topically applied photosensitizer for photodynamic therapy (PDT) of cervical intraepithelial neoplasia (CIN). ## Study Designs/Materials and Methods Forty women, who were at least 18
Fifty biopsies from high-grade squamous intraepithelial lesions (HG-SIL) and 14 cervical carcinoma biopsies from Greek women were screened for the presence of human papillomavirus (HPV) DNA sequences by Southern blot hybridization and by the polymerase chain reaction (PCR) for the presence of differ