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Regression of cardiac hypertrophy in cyp1a1ren-2 transgenic rats

✍ Scribed by Barbara S. Peters; Rami Dornaika; Norbert Hosten; Stefan Hadlich; John J. Mullins; Jörg Peters; Rainer Rettig


Book ID
112133096
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
877 KB
Volume
36
Category
Article
ISSN
1053-1807

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi