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Regression models for association studies of quantitative trait loci in humans

✍ Scribed by Lon R. Cardon; Gonçalo R. Abecasis

Book ID
114432562
Publisher
John Wiley and Sons
Year
2000
Weight
204 KB
Volume
1
Category
Article
ISSN
1466-920X

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Framework for identifying quantitative trait loci in association studies using structural equation modeling
✍ Edwin J.C.G. van den Oord 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB 👁 1 views

In this article, we suggest a framework for identifying quantitative trait loci (QTL) in association studies using structural equation modeling. Two tests to detect QTLs and estimate the proportion of variance they explain are discussed. The first test assumes that there is no population admixture a