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Registration of images from sequential MR studies of the brain

✍ Scribed by Sarah J. Nelson; Allen B. Nalbandian; Evelyn Proctor; Daniel B. Vigneron

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
918 KB
Volume
4
Category
Article
ISSN
1053-1807

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

For sequential studies of patients with brain tumors, the authors have designed an automated registration procedure for intra‐ and interexamination alignment of magnetic resonance images. This was evaluated with artificially misregistered data and data from repeat studies of six healthy volunteers and six brain tumor patients. In a subset of cases, a manual procedure based on matching of neuroanatomic landmarks was also applied for comparison. The results showed that the technique is robust and reproducible, giving an accuracy in the range of 1–2 mm, which corresponded to the spatial resolution of the images. Subject motion between imaging sequences within the same study was negligible, although adjustments (one to two section thicknesses) were required in the z direction to correlate multisection and volume images and to allow accurate image segmentation. For alignment between sequential volunteer and patient examinations, translations of up to 22 mm and rotations in the x, y, and z axes of up to 9Β° were required. This alignment procedure may be valuable in numerous aspects of treatment planning and patient follow‐up.

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