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Regiospecificity of Nucleophilic Substitution in 4,6-Dinitro-1-phenyl-1H-indazole.

✍ Scribed by A. M. Starosotnikov; A. V. Lobach; V. V. Kachala; S. A. Shevelev


Publisher
John Wiley and Sons
Year
2005
Weight
133 KB
Volume
36
Category
Article
ISSN
0931-7597

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Synthesis of 4-amino-3,5-dinitro-1H-pyra
✍ Robert D. Schmidt; Gregory S. Lee; Philip F. Pagoria; Alexander R. Mitchell; Ric πŸ“‚ Article πŸ“… 2001 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 47 KB

## Abstract A novel synthesis of the title compound was achieved by direct animation using Vicarious Nucleophilic Substitution (VNS) methodology. Reaction of 1,1,1‐trimethylhydrazinium iodide with 3,5‐dinitropyrazole in DMSO produces 4‐amino‐3,5‐dinitro‐1__H__‐pyrazole as a 1:1 crystal solvate with