Regiospecific ring opening of N-acylaziridines by neutral hydrolysis

✍ Scribed by Néji Besbes

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 116 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00979-x

✦ Synopsis

The neutral hydrolysis of N-acyl-2,2-dimethylaziridines gave rise to the amidoalcohols in 76-91% overall yields. These products resulted from the specific cleavage of the C-2-N bond.