Regiospecific oxidation of an alkyl group of aromatic amine to carbonyl group by DDQ in aq. medium

✍ Scribed by Madhav S. Mane; Ravi S. Balaskar; Sandip N. Gavade; Pramod N. Pabrekar; Murlidhar S. Shingare; Dhananjay V. Mane

• Publisher: Chinese Electronic Periodical Services
• Year: 2011
• Tongue: English
• Weight: 128 KB
• Volume: 22
• Category: Article
• ISSN: 1001-8417
• DOI: 10.1016/j.cclet.2011.03.016

✦ Synopsis

The regiospecific oxidation of alkyl group of both sterically hindered and unhindered aromatic amine to corresponding carbonyl compound was done in aq. medium by using DDQ. The optimized reaction protocol was found to be most simple, high yielding and novel method for oxidation of alkyl group of aromatic amine in to its carbonyl compound.