Threo-selective aldol condensations of l
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Yoshinori Yamamoto; Hidetaka Yatagai; Kazuhiro Maruyama
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Article
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1982
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Elsevier Science
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French
โ 164 KB
The reaction of preformed lithium enolates in the presence of trialkylboranes, such as Et3B and n-Bu3B, with aldehydes leads to product mixtures rich in the more stable threo aldol. The development of the diastereoselective synthesis of t3-hydroxycarbonyl compounds as a basic synthetic block for ma