Regioselectivity of Vinyl Sulfone Based 1,3-Dipolar Cycloaddition Reactions with Sugar Azides by Computational and Experimental Studies
β Scribed by Sahu, Debashis; Dey, Santu; Pathak, Tanmaya; Ganguly, Bishwajit
- Book ID
- 121856148
- Publisher
- American Chemical Society
- Year
- 2014
- Tongue
- English
- Weight
- 864 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1523-7060
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π SIMILAR VOLUMES
The 1,3-dipolar cyclosddition reaction of pyrazolidinium ylide 1 vith substituted vinyl sulfones 5 warn studied. Elimination of benzeneaulfinic acid from the resulting cycloadducts gave rise to bicyclic pyrazolidiaones 3. The (E)-olefin isomers vere found to undergo cycloadditioo in a highly regiose
## Abstract The reaction mechanism and solventβdependant regioselectivity of 1,3βdipolar cycloaddition reactions between azide and acetylene derivatives have been studied using computational methods. The two possible reaction transition states were located. Geometry and NBO analysis found that the