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Regioselectivity of fluoride ion-induced intramolecular nucleophilic cyclization of heptafluoronaphthyl sulfur diimides 2NfFNSNSiMe3 and 2NfFSNSNS1Me3

✍ Scribed by Irina Yu. Bagryanskaya; Yuri V. Gatilov; Alexey O. Miller; Makhmut M. Shakirov; Andrey V. Zibarev


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
373 KB
Volume
5
Category
Article
ISSN
1042-7163

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✦ Synopsis


Abstract

The title reaction is highly regioselective, leading in both cases to 4,5,6,7,8,9‐hexafluoronaphtho[1,2‐c]‐[1,2,5]thiadiazole (whose struture is confirmed by X‐ray structure analysis) and 4,5,6,7,8,9‐hexafluoronaphtho[2,3‐c][1,2,5]thiadiazole in ∼94 : 6 ratio. The preferred direction of cyclization is consistent with final product thermodynamics as well as factors of kinetic control for orbital‐controlled reactions (calculated by use of frontier MOs theory).