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Regioselectivity in the Intramolecular Heck Reaction of a Series of Cyclic Sulfonamides: An Experimental and Computational Study

✍ Scribed by Kimberly Geoghegan; Dr. Paul Evans; Prof. Isabel Rozas; Prof. Ibon Alkorta


Book ID
115551577
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
1008 KB
Volume
18
Category
Article
ISSN
0947-6539

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Regioselectivity of the Claisen Rearrang
✍ Catherine L. Lucas; Prof.β€…Dr. Barry Lygo; Prof.β€…Dr. Alexander J. Blake; Dr. Will πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 305 KB πŸ‘ 1 views

## Abstract A study of the regioselectivity of the Claisen rearrangement of __meta__‐allyloxy aryl ketones showed that the electron‐withdrawing carbonyl group has a major influence and strongly directs rearrangement to the more hindered __ortho__ position. However, when the ketone is part of a ring