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Regioselectivity in the glutathione-phenylglycidyl ether reaction: 1H NMR characterization of the adduct

✍ Scribed by André De Bruyn; Denis De Keukeleire; Elfride van Den Eeckhout; Willy Baeyens


Book ID
101766043
Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
213 KB
Volume
92
Category
Article
ISSN
0037-9646

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✦ Synopsis


A detailed 360 MHz ' H NMR analysis leads to the unambiguous structural identification of the compound , which is regioselectivelv formed in the chemical and enzymatical reactions between glutathione and phenvlqlycidyl ether. The thiol group attacks preferentially the least substituted oxirane carbon atom.


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